Precision medicine: impacting through innovative technology

Background:

The focus of this competition is to support the development of precision medicine technologies.  We define precision medicine as better targeting of treatments for patients by combining clinical knowledge with advances in diagnostic techniques and data analysis. Precision medicine is also referred to as stratified medicine or personalised medicine.

You may focus either on:

  • feasibility to help companies assess the research, development and adoption issues their concept will need to address and the likelihood of success
  • research and development to help companies develop and trial precision medicine technology

Feasibility studies

You must be able to analyse and evaluate your concept’s potential, identify the requirements and resources needed to develop the technology, and establish the prospects of success. A project can focus on feasibility studies or industrial research. The work undertaken during a feasibility study can vary, but it could cover:

1. Clarifying the value proposition of the concept to help healthcare providers and other customers to understand its attractiveness. This could include determining:

  • patient and end user needs
  • the required changes to patient pathways
  • commissioning and procurement options
  • health economics
  • adoption drivers

2. Initial technical activities including areas such as:

  • developing prototypes and proofs of concept
  • collecting further data on the use of biomarkers to distinguish between different patient groups
  • refining algorithms to improve patient stratification

3. Assessing the required levels of technical performance to be a success, covering areas such as:

  • analytical performance
  • diagnostic sensitivity and specificity

4. Determining what information will need to be collated from a regulatory or health technology assessment perspective.

These projects will allow companies to map out and understand the technical, operational, clinical, regulatory and adoption challenges they will need to meet.

Research and development

For research and development applications, you can develop and trial precision medicine technologies. Your project may focus on industrial research or experimental development, depending on the challenge identified. It can have work packages in different research categories if necessary. You should evidence your understanding of the potential mitigation strategies for the technical, operational, clinical, regulatory and adoption challenges related to the project.

Your project must look to advance precision medicine by guiding decision-making using one of the following approaches:

  1. Developing tools to better integrate informatics and data.
  2. Establishing precision medicine clinical trials.
  3. Developing rapid diagnostics to inform better treatment decisions.

We would encourage you to work with the appropriate UK organisation in your area of precision medicine, such as:

  • Academic Health Science Networks
  • Catapults and other research and technology organisations
  • the molecular pathology nodes supported by the MRC and EPSRC
  • Diagnostic Evidence Co-operatives (soon to be MedTech and In Vitro Diagnostic Co-operatives)
  • market access companies

Key Dates:

11 September 2017 Competition opens

25 October 2017 12:00pm Competition closes

If you are interested in this competition?

Please email the Innovation SuperNetwork team at angela@supernetwork.org.uk or complete the form below so we can help you and guide you through the application process.

(Direct links – please cut and paste into browser: https://apply-for-innovation-funding.service.gov.uk/competition/48/overview)

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Partners

Our work is only possible with the support of our local and national partners, including Innovate UK, the Knowledge Transfer Network, the North East LEP, Northumbrian WaterNorth East BIC, and Reece Innovation with part funding from the European Regional Development Fund.
Huge thanks go to all our partners.